[which is] a significant step toward human clinical trials.
“To our knowledge, this study is the first to demonstrate the effective excision of HIV-1 proviral DNA from the host genome in pre-clinical animal models [using this method].” However, they added that “gene delivery efficiency …
“Here, we demonstrate the feasibility and efficiency of excising the HIV-1 provirus in three different animal models,” they wrote.
“Excision of HIV-1 proviral DNA by [this method in a living animal] in solid tissues/organs can be achieved …
remains an obstacle to overcome” in a living animal.
The researchers told the that the next step would be to repeat the study in primates, described as a “more suitable animal model where HIV infection induces disease” before the “eventual goal” of human clinical trials.
In one of the most highly publicised statements, in October 2003, the President of the Vatican's Pontifical Council for the Family, Cardinal Alfonso Lopez Trujillo, said: "The AIDS virus is roughly 450 times smaller than the spermatozoon.